Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.58 |
| ▸ | CTSK | P43235 | 12/20 | 0.58 |
| ▸ | CTSB | P07858 | 4/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25419654 | 0.91 | CTSS (0.58) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL6164303 | 0.91 | CTSS (0.58) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL29907936 | 0.88 | CTSS (0.62) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL3748888 | 0.88 | CTSS (0.62) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL3748882 | 0.88 | CTSS (0.62) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL5067241 | 0.88 | CTSS (0.62) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL6163123 | 0.87 | CTSS (0.58) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL18930239 | 0.86 | CTSS (0.56) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL4839075 | 0.83 | CTSS (0.53) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL4499875 | 0.83 | CTSS (0.53) | CTSSCTSKCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102140-A1 | TMPRSS2 INHIBITORS AND METHODS OF USE | TOPSPIN THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |