Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LIPC | P11150 | 1/20 | 0.44 |
| ▸ | GPR6 | P46095 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30446157 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MAPTLIPCHPGDALOX5 | |
| SCHEMBL30446572 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MAPTLIPCHPGDALOX5 | |
| SCHEMBL30446494 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MAPTLIPCHPGDALOX5 | |
| SCHEMBL25420795 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MAPTLIPCHPGDALOX5 | |
| Hydrochloric Acid SCHEMBL25420223 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MAPTLIPCHPGDALOX5 | |
| Hydrochloric Acid SCHEMBL25419669 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MAPTLIPCHPGDALOX5 | |
| Hydrochloric Acid SCHEMBL30446963 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MAPTLIPCHPGDALOX5 | |
| Hydrochloric Acid SCHEMBL25419927 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MAPTLIPCHPGDALOX5 | |
| SCHEMBL25421104 | 0.75 | MAPT (0.44) | ALDH1A1MAPTLIPCCYP1A2CYP2C19 | |
| SCHEMBL30446041 | 0.75 | MAPT (0.44) | ALDH1A1MAPTLIPCCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102140-A1 | TMPRSS2 INHIBITORS AND METHODS OF USE | TOPSPIN THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |