Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30472607 | 0.87 | CYP2C19 (0.44) | RAB9ALMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL25422589 | 0.85 | CNR1 (0.42) | RAB9ALMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL25439503 | 0.73 | CYP2C19 (0.46) | RAB9ALMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL30472671 | 0.72 | CYP2C19 (0.42) | RAB9ALMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL30472622 | 0.72 | CYP2C19 (0.42) | RAB9ALMNASMN1; SMN2MAPTHTT | |
| SCHEMBL30472667 | 0.72 | CYP2C19 (0.42) | RAB9ALMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL889076 | 0.71 | HTT (0.54) | RAB9ALMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL889034 | 0.69 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL14182719 | 0.67 | MAOA (0.52) | RAB9ALMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL14183010 | 0.67 | ITK (0.45) | RAB9ALMNASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118253-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-06-29 | — | — | WO | disclosed |