Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.36 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | MTR | Q99707 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25421297 | 0.96 | CRBN (0.36) | CRBNIKZF1CSNK1A1HTR2AHTR2C | |
| SCHEMBL25421672 | 0.88 | CRBN (0.36) | CRBNIKZF1CSNK1A1HTR2AHTR2C | |
| SCHEMBL25421957 | 0.86 | CRBN (0.36) | CRBNIKZF1CSNK1A1HTR2AHTR2C | |
| SCHEMBL25423775 | 0.86 | HTR2C (0.39) | CRBNIKZF1CSNK1A1HTR2AHTR2C | |
| SCHEMBL25422129 | 0.85 | HTR2C (0.38) | CRBNIKZF1CSNK1A1HTR2AHTR2C | |
| SCHEMBL25419396 | 0.84 | HTR2C (0.39) | CRBNIKZF1CSNK1A1HTR2AHTR2C | |
| SCHEMBL25420904 | 0.84 | HTR2A (0.39) | CRBNIKZF1CSNK1A1HTR2AHTR2C | |
| SCHEMBL25231071 | 0.84 | MAPK1 (0.38) | CRBNIKZF1CSNK1A1HTR2AHTR2C | |
| SCHEMBL25422666 | 0.81 | MAOA (0.35) | CRBNIKZF1HTR2AHTR2CHTR2B | |
| SCHEMBL26094954 | 0.81 | MAPK1 (0.35) | CRBNIKZF1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |