Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | KIF11 | P52732 | 12/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25424698 | 0.93 | HTR2A (0.51) | HTR2AHTR2CKIF11PDE5AHTR2B | |
| SCHEMBL25426227 | 0.91 | KIF11 (0.47) | HTR2AHTR2CKIF11PDE5A | |
| SCHEMBL25288120 | 0.89 | HTR2A (0.48) | HTR2AHTR2CKIF11PDE5AHTR2B | |
| SCHEMBL25425692 | 0.88 | HTR2C (0.47) | HTR2AHTR2CKIF11PDE5AHTR2B | |
| SCHEMBL25423948 | 0.87 | HTR2A (0.55) | HTR2AHTR2CKIF11PDE5AHTR2B | |
| SCHEMBL25424450 | 0.87 | HTR2A (0.51) | HTR2AHTR2CKIF11PDE5AHTR2B | |
| SCHEMBL25425921 | 0.87 | HTR2A (0.51) | HTR2AHTR2CKIF11PDE5AHTR2B | |
| SCHEMBL25423359 | 0.86 | PDE5A (0.42) | HTR2AHTR2CKIF11PDE5A | |
| SCHEMBL25423471 | 0.83 | HTR2A (0.51) | HTR2AHTR2CKIF11PDE5AHTR2B | |
| SCHEMBL25422019 | 0.82 | KIF11 (0.46) | HTR2AHTR2CKIF11PDE5AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130070-A2 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | claimed |