Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.47 |
| ▸ | KIF11 | P52732 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25425640 | 0.90 | PDE5A (0.43) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25423259 | 0.89 | PDE5A (0.45) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25426810 | 0.88 | PDE5A (0.43) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25424507 | 0.86 | PDE5A (0.41) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25426658 | 0.85 | PDE5A (0.43) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25425224 | 0.85 | PDE5A (0.43) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25425384 | 0.85 | PDE5A (0.42) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25422423 | 0.84 | PDE5A (0.42) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25425814 | 0.83 | PDE5A (0.48) | PDE5AKIF11HTR2AHTR2CTP53 | |
| SCHEMBL25422610 | 0.82 | PDE5A (0.52) | PDE5AKIF11HTR2AHTR2CTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130070-A2 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | claimed |