⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2538890 | 1.00 | LMNA (0.41) | — | |
| SCHEMBL2245103 | 1.00 | LMNA (0.41) | — | |
| SCHEMBL8985496 | 0.97 | — | — | |
| SCHEMBL1460812 | 0.97 | — | — | |
| SCHEMBL1460813 | 0.97 | — | — | |
| SCHEMBL1721189 | 0.88 | — | — | |
| SCHEMBL21104456 | 0.88 | — | — | |
| SCHEMBL2249178 | 0.82 | MEN1 (0.42) | — | |
| SCHEMBL30110429 | 0.82 | LMNA (0.37) | — | |
| SCHEMBL852700 | 0.77 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115212922-B | Catalyst composition for alpha-olefin polymerization and preparation and application thereof | 中国石油天然气股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| US-8044070-B2 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20100210637-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | MSD K.K. (JP) | 2010-08-19 | — | — | US | disclosed |
| US-7595316-B2 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-09-29 | — | — | US | disclosed |
| US-20060178375-A1 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1642898-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-04-05 | — | — | EP | disclosed |
| EP-0802900-B1 | ANTIARRHYTHMIC (S)-ENANTIOMERS OF METHANESULFONAMIDES | UPJOHN CO (US) | 2000-02-16 | — | — | EP | disclosed |
| US-5874475-A | DO NOT HAVE SIDE EFFECT OF PRODUCING POLYMORPHIC VENTRICULAR TACHYCARDIA | PHARMACIA & UPJOHN COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0802900-A1 | ANTIARRHYTHMIC (S)-ENANTIOMERS OF METHANESULFONAMIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-10-29 | — | — | EP | disclosed |
| EP-0781273-A1 | 4-(4-METHANESULFONAMIDOPHENYL)BUTYLAMINE DERIVATIVES WITH ANTIARRHYTHMIC ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996021643-A1 | ANTIARRHYTHMIC (S)-ENANTIOMERS OF METHANESULFONAMIDES | PHARMACIA & UPJOHN COMPANY (US) | 1996-07-18 | — | — | WO | disclosed |
| WO-1996008471-A1 | 4-(4-METHANESULFONAMIDOPHENYL)BUTYLAMINE DERIVATIVES WITH ANTIARRHYTHMIC ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 1996-03-21 | — | — | WO | disclosed |