Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25888058 | 0.85 | TOP2A (0.36) | TOP2ATOP2B | |
| SCHEMBL25888068 | 0.79 | TOP2A (0.33) | TOP2ATOP2B | |
| SCHEMBL25427194 | 0.77 | LRRK2 (0.31) | — | |
| SCHEMBL30510510 | 0.77 | LRRK2 (0.31) | — | |
| SCHEMBL25427196 | 0.77 | LRRK2 (0.31) | — | |
| SCHEMBL25888052 | 0.77 | TOP2A (0.34) | TOP2ATOP2B | |
| SCHEMBL25427926 | 0.76 | DPP4 (0.37) | TOP2ATOP2B | |
| SCHEMBL30510604 | 0.76 | DPP4 (0.37) | TOP2ATOP2B | |
| SCHEMBL30510577 | 0.73 | PIK3CG (0.31) | — | |
| SCHEMBL25424714 | 0.73 | PIK3CG (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122093-A1 | REV-ERB AGONISTS FOR TH17-MEDIATED INFLAMMATORY DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-29 | — | — | WO | disclosed |