Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 7/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25427926 | 1.00 | DPP4 (0.37) | DPP4ACHEHTR3AKEAP1NFE2L2 | |
| SCHEMBL25428026 | 0.87 | HTR3A (0.38) | DPP4HTR3AKEAP1NFE2L2 | |
| SCHEMBL30510530 | 0.87 | HTR3A (0.38) | DPP4HTR3AKEAP1NFE2L2 | |
| SCHEMBL30510577 | 0.80 | PIK3CG (0.31) | DPP4HTR3APIK3CGCHRM2DRD1 | |
| SCHEMBL25424717 | 0.80 | PIK3CG (0.31) | DPP4HTR3APIK3CGCHRM2DRD1 | |
| SCHEMBL25424714 | 0.80 | PIK3CG (0.31) | DPP4HTR3APIK3CGCHRM2DRD1 | |
| SCHEMBL25888048 | 0.79 | DPP4 (0.30) | DPP4 | |
| SCHEMBL27789261 | 0.78 | DPP4 (0.52) | DPP4TOP2ATOP2BPIK3CGCHRM2 | |
| SCHEMBL500472 | 0.76 | DPP4 (0.57) | DPP4TOP2ATOP2BPIK3CGCHRM2 | |
| SCHEMBL25425918 | 0.76 | TOP2A (0.35) | TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122093-A1 | REV-ERB AGONISTS FOR TH17-MEDIATED INFLAMMATORY DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-29 | — | — | WO | disclosed |