Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25246666 | 0.89 | HTR2A (0.57) | HTR2A | |
| SCHEMBL25769697 | 0.84 | HTR2A (0.70) | HTR2A | |
| SCHEMBL25242657 | 0.82 | HTR2A (0.60) | HTR2AAR | |
| SCHEMBL25250221 | 0.82 | HTR2A (0.60) | HTR2AKDM4EHSD17B10 | |
| SCHEMBL30548025 | 0.81 | HTR2A (0.66) | HTR2AAR | |
| SCHEMBL25288178 | 0.81 | HTR2A (0.66) | HTR2AAR | |
| SCHEMBL25771290 | 0.81 | HTR2A (0.59) | HTR2A | |
| SCHEMBL25298709 | 0.79 | HTR2A (0.57) | HTR2A | |
| SCHEMBL25255683 | 0.79 | HTR2A (0.57) | HTR2A | |
| SCHEMBL25290785 | 0.79 | HTR2A (0.57) | HTR2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447954-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | Icahn School of Medicine at Mount Sinai (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114472-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114472-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-06-22 | — | — | WO | disclosed |