Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25426315 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 | |
| SCHEMBL25315976 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 | |
| SCHEMBL25890398 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 | |
| SCHEMBL25315988 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 | |
| SCHEMBL25317874 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL30534577 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 | |
| SCHEMBL25317238 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 | |
| SCHEMBL25317014 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 | |
| SCHEMBL25316554 | 0.83 | PTGDR2 (0.41) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 | |
| SCHEMBL25891914 | 0.82 | PTGDR2 (0.41) | ALDH1A1HSD11B1ESR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469155-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023141323-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-07-27 | — | — | WO | disclosed |