Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 6/20 | 0.41 |
| ▸ | KIF11 | P52732 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25426810 | 0.94 | PDE5A (0.43) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25423259 | 0.92 | PDE5A (0.45) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25425269 | 0.92 | PDE5A (0.40) | PDE5AKIF11LMNASTAT3HTR2A | |
| Formic Acid SCHEMBL25424187 | 0.90 | PDE5A (0.40) | PDE5AKIF11LMNASTAT3SIRT1 | |
| SCHEMBL25423733 | 0.89 | PDE5A (0.40) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25425224 | 0.87 | PDE5A (0.43) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25425384 | 0.87 | PDE5A (0.42) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25425640 | 0.86 | PDE5A (0.43) | PDE5AKIF11LMNASTAT3HTR2A | |
| SCHEMBL25423987 | 0.86 | KIF11 (0.43) | PDE5AKIF11HTR2AHTR2CSIRT1 | |
| SCHEMBL25427222 | 0.86 | PDE5A (0.42) | PDE5AKIF11LMNASTAT3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130070-A2 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | claimed |