Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PLEC | Q15149 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 11/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA2 | P00918 | 10/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29487272 | 0.86 | USP2 (0.51) | USP2MEN1POLBKMT2AATM | |
| Bromide SCHEMBL25262541 | 0.86 | USP2 (0.51) | USP2MEN1POLBKMT2AATM | |
| Bromide SCHEMBL25426442 | 0.81 | USP2 (0.53) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL29591827 | 0.78 | USP2 (0.76) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL107875 | 0.78 | USP2 (0.76) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL29781098 | 0.78 | USP2 (0.76) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL7591292 | 0.77 | USP2 (0.74) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL8451224 | 0.77 | USP2 (0.74) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL29594855 | 0.76 | USP2 (0.65) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL7591289 | 0.76 | USP2 (0.65) | USP2MEN1POLBKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466254-A1 | PHENAZINE COMPOUND FOR MEASURING BACTERIAL EFFLUX | Université d'Aix Marseille (FR) | 2024-11-27 | — | — | EP | claimed |
| WO-2023139263-A1 | PHENAZINE COMPOUND FOR MEASURING BACTERIAL EFFLUX | UNIVERSITE D'AIX-MARSEILLE (FR) | 2023-07-27 | — | — | WO | claimed |
| EP-4466254-A1 | PHENAZINE COMPOUND FOR MEASURING BACTERIAL EFFLUX | Université d'Aix Marseille (FR) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139263-A1 | PHENAZINE COMPOUND FOR MEASURING BACTERIAL EFFLUX | UNIVERSITE D'AIX-MARSEILLE (FR) | 2023-07-27 | — | — | WO | disclosed |