Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 9/20 | 0.52 |
| ▸ | CA2 known ✓ | P00918 | 9/20 | 0.52 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | PLEC | Q15149 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 11/20 | 0.52 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29594855 | 1.00 | USP2 (0.65) | USP2MEN1KMT2APOLBATM | |
| Fluorescein Sodium SCHEMBL29355465 | 0.89 | USP2 (0.50) | USP2MEN1KMT2APOLBATM | |
| Fluorescein Sodium SCHEMBL264060 | 0.89 | USP2 (0.50) | USP2MEN1KMT2APOLBATM | |
| Fluorescein Sodium SCHEMBL29364968 | 0.89 | USP2 (0.50) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL29591827 | 0.88 | USP2 (0.76) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL107875 | 0.88 | USP2 (0.76) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL29781098 | 0.88 | USP2 (0.76) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL7591292 | 0.87 | USP2 (0.74) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL14417443 | 0.87 | USP2 (0.67) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL8451224 | 0.87 | USP2 (0.74) | USP2MEN1KMT2APOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017344-B1 | LIQUID MANAGEMENT FILM FOR ABSORBENT ARTICLES | MINNESOTA MINING & MFG (US) | 2002-10-30 | — | — | EP | disclosed |
| US-6372954-B1 | MEMBER COMPRISING FILM OF IMPERMEABLE MATERIAL HAVING AT LEAST ONE MICROSTRUCTURE-BEARING HYDROPHILIC SURFACE, WITH PLURALITY OF LATERALLY SPACED APART V-SHAPED GROOVES, THAT PROMOTES DIRECTIONAL SPREADING OF LIQUIDS | 3M INNOVATIVE PROPERTIES COMPANY | 2002-04-16 | — | — | US | disclosed |
| EP-1017344-A1 | LIQUID MANAGEMENT FILM FOR ABSORBENT ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-0617604-B1 | LIQUID MANAGEMENT MEMBER FOR ABSORBENT ARTICLES | MINNESOTA MINING & MFG (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1999009923-A1 | LIQUID MANAGEMENT FILM FOR ABSORBENT ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| US-5728446-A | GROOVES | MINNESOTA MINING AND MANUFACTURING COMPANY | 1998-03-17 | — | — | US | disclosed |
| US-5514120-A | Liquid management member for absorbent articles | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0617604-A1 | LIQUID MANAGEMENT MEMBER FOR ABSORBENT ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-10-05 | — | — | EP | disclosed |
| WO-1993011727-A1 | LIQUID MANAGEMENT MEMBER FOR ABSORBENT ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-06-24 | — | — | WO | disclosed |