Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butyrolactone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyrolactone SCHEMBL7686323 | 1.00 | CA1 (0.67) | CA1CA9LMNATSHRALDH1A1 | |
| Butyrolactone SCHEMBL3638548 | 0.95 | CA1 (0.61) | CA1CA9LMNATSHRALDH1A1 | |
| Bicarbonate SCHEMBL2495473 | 0.92 | CA1 (0.80) | CA1CA9LMNATSHRALDH1A1 | |
| Bicarbonate SCHEMBL6753674 | 0.92 | CA1 (0.80) | CA1CA9LMNATSHRALDH1A1 | |
| Butyrolactone SCHEMBL28099382 | 0.90 | CA1 (0.61) | CA1CA9LMNATSHRALDH1A1 | |
| Butyrolactone SCHEMBL6571306 | 0.90 | CA1 (0.61) | CA1CA9LMNATSHRALDH1A1 | |
| Bicarbonate SCHEMBL8606312 | 0.90 | CA1 (0.76) | CA1CA9LMNATSHRALDH1A1 | |
| Butyrolactone SCHEMBL10999881 | 0.90 | CA1 (0.61) | CA1CA9LMNATSHRALDH1A1 | |
| Bicarbonate SCHEMBL2501163 | 0.90 | CA1 (0.67) | CA1CA9LMNATSHRALDH1A1 | |
| Bicarbonate SCHEMBL980234 | 0.90 | CA1 (0.67) | CA1CA9LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023127433-A1 | FILM, FILM MANUFACTURING METHOD, AND LAMINATE | 富士フイルム株式会社 | 2023-07-06 | — | — | WO | disclosed |
| CN-109786670-B | Preparation method of high-first-efficiency lithium ion secondary battery negative electrode active material | 南开大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-102248713-B | Polyene microporous multilayer diaphragm and manufacturing method thereof | FOSHAN DONGHANG OPTIC ELECTRIC TECHNOLOGY CO LTD | 2014-12-31 | — | — | CN | disclosed |
| CN-102248713-A | Polyene microporous multilayer diaphragm and manufacturing method thereof | FOSHAN DONGHANG OPTIC ELECTRIC TECHNOLOGY CO LTD | 2011-11-23 | — | — | CN | disclosed |
| CN-100358902-C | Synthesis of binuclear metal complex compound and its catalyzed copolymerization and cycloaddition reaction of carbon dioxide and epoxide | SHANGHAI INST ORGANIC CHEM (CN) | 2008-01-02 | — | — | CN | disclosed |
| CN-1897329-A | Microporous polyolefin laminated diaphragm for lithium-ion battery and its production | SHENGCHAO AUTOMATION SCIENCE A (CN) | 2007-01-17 | — | — | CN | disclosed |
| CN-1786004-A | Synthesis of binuclear metal complex compound and its catalyzed copolymerization and cycloaddition reaction of carbon dioxide and epoxide | SHANGHAI INST ORGANIC CHEM (CN) | 2006-06-14 | — | — | CN | disclosed |