Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22054806 | 0.80 | DPP4 (0.50) | DPP4DPP8NAMPTNOTUMCDK1 | |
| SCHEMBL14753226 | 0.80 | DPP4 (0.52) | DPP4DPP8NAMPTNOTUMCDK1 | |
| SCHEMBL30980046 | 0.79 | NAMPT (0.49) | DPP4DPP8NAMPTNOTUMCDK1 | |
| SCHEMBL25429882 | 0.78 | SCD (0.46) | NAMPTCDK1MYT1SPRKMT2A | |
| SCHEMBL25428126 | 0.75 | NAMPT (0.44) | NAMPTCDK1MYT1SPRKMT2A | |
| SCHEMBL12332202 | 0.74 | NAMPT (0.48) | DPP4DPP8NAMPTNOTUMCDK1 | |
| SCHEMBL22977583 | 0.74 | DPP4 (0.49) | DPP4DPP8NAMPTNOTUMCDK1 | |
| SCHEMBL22054673 | 0.74 | DPP4 (0.61) | DPP4DPP8NAMPTNOTUMCDK1 | |
| SCHEMBL25430234 | 0.73 | NOTUM (0.43) | DPP4DPP8NOTUM | |
| SCHEMBL21555894 | 0.73 | DPP4 (0.55) | DPP4DPP8NAMPTNOTUMCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |