Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25428013 | 0.75 | DPP4 (0.48) | NAMPTCDK1MYT1SPRKMT2A | |
| Trifluoroacetic Acid SCHEMBL25430229 | 0.75 | NAMPT (0.39) | NAMPTCDK1MYT1SPRSCN9A | |
| SCHEMBL30878026 | 0.74 | NAMPT (0.50) | NAMPTCDK1MYT1SPRSYK | |
| SCHEMBL25429882 | 0.72 | SCD (0.46) | NAMPTCDK1MYT1SPRKMT2A | |
| SCHEMBL25432305 | 0.71 | SCN9A (0.41) | NAMPTCDK1MYT1SPRKMT2A | |
| SCHEMBL25430234 | 0.65 | NOTUM (0.43) | — | |
| SCHEMBL2907861 | 0.64 | ATM (0.48) | RAB9AL3MBTL1 | |
| SCHEMBL19813202 | 0.63 | KMT2A (0.35) | KMT2AMEN1ITGB3ITGA2BPRMT3 | |
| SCHEMBL25429026 | 0.62 | DPP4 (0.56) | — | |
| SCHEMBL16093860 | 0.62 | GRM5 (0.44) | KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |