Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25424367 | 0.93 | PTGER2 (0.41) | PTGER2QPCTDGAT2SLC2A1MAOB | |
| SCHEMBL25425923 | 0.91 | PTGER2 (0.43) | PTGER2QPCTDGAT2SLC2A1CETP | |
| SCHEMBL25298286 | 0.89 | PTGER2 (0.41) | PTGER2QPCTDGAT2SLC2A1KDM4E | |
| SCHEMBL30245668 | 0.88 | QPCT (0.47) | QPCTSLC2A1CETPMAOBCALM1 | |
| SCHEMBL25426048 | 0.86 | QPCT (0.40) | PTGER2QPCTDGAT2SLC2A1EGLN1 | |
| SCHEMBL25425996 | 0.86 | QPCT (0.41) | PTGER2QPCTDGAT2SLC2A1CETP | |
| SCHEMBL25425531 | 0.86 | QPCT (0.41) | PTGER2QPCTDGAT2SLC2A1EGLN1 | |
| SCHEMBL25424668 | 0.86 | PTGER2 (0.40) | PTGER2QPCTDGAT2SLC2A1CETP | |
| SCHEMBL25427950 | 0.85 | ALDH1A1 (0.40) | — | |
| SCHEMBL30245561 | 0.85 | MAPT (0.40) | QPCTCETPKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | claimed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | claimed |
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |