Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223854 | 0.85 | DPP4 (0.59) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL25937808 | 0.85 | DPP4 (0.49) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL22897326 | 0.85 | DPP4 (0.55) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL22897337 | 0.84 | DPP4 (0.52) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL11948486 | 0.83 | DPP4 (0.60) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL28425771 | 0.83 | DPP4 (0.57) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL10025046 | 0.82 | DPP4 (0.59) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL25430234 | 0.82 | NOTUM (0.43) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL332389 | 0.82 | DPP4 (0.59) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL25937810 | 0.82 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |