Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937798 | 0.85 | ALDH1A1 (0.47) | DPP4DPP8SIGMAR1 | |
| SCHEMBL25429026 | 0.85 | DPP4 (0.56) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3714776 | 0.81 | DPP4 (0.52) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1262930 | 0.81 | DPP4 (0.52) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3134930 | 0.81 | CYP8B1 (0.54) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1262025 | 0.81 | DPP4 (0.51) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3712598 | 0.81 | DPP4 (0.51) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL2555253 | 0.79 | DPP4 (0.51) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL12285638 | 0.79 | DPP4 (0.71) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL28425771 | 0.78 | DPP4 (0.57) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |