Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 6/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937522 | 0.91 | SCD (0.46) | P2RX7SCDSCD5RIPK1VNN1 | |
| Trifluoroacetic Acid SCHEMBL30557635 | 0.80 | DPP4 (0.54) | NAMPTDPP4DPP8CDK1MYT1 | |
| SCHEMBL13195585 | 0.76 | SCD (0.46) | P2RX7SCDSCD5RIPK1VNN1 | |
| SCHEMBL14753264 | 0.76 | SCD (0.46) | P2RX7SCDSCD5RIPK1VNN1 | |
| SCHEMBL21410419 | 0.76 | SCD (0.53) | P2RX7SCDSCD5RIPK1VNN1 | |
| SCHEMBL13584658 | 0.75 | SCD (0.44) | P2RX7SCDSCD5RIPK1VNN1 | |
| SCHEMBL25429882 | 0.75 | SCD (0.46) | P2RX7SCDSCD5RIPK1VNN1 | |
| Trifluoroacetic Acid SCHEMBL25430229 | 0.74 | NAMPT (0.39) | NAMPTDPP4DPP8CDK1MYT1 | |
| SCHEMBL31622168 | 0.74 | SCD (0.49) | P2RX7SCDSCD5RIPK1VNN1 | |
| SCHEMBL2303112 | 0.73 | PARP1 (0.43) | P2RX7SCDSCD5RIPK1VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |