Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937534 | 0.91 | DPP4 (0.55) | DPP4DPP8NOTUMNAMPTSCN9A | |
| Trifluoroacetic Acid SCHEMBL25429290 | 0.80 | P2RX7 (0.47) | DPP4DPP8NAMPTDPP9CDK1 | |
| Trifluoroacetic Acid SCHEMBL25430229 | 0.77 | NAMPT (0.39) | DPP4DPP8NAMPTSCN9ACDK1 | |
| SCHEMBL22054806 | 0.77 | DPP4 (0.50) | DPP4DPP8NOTUMNAMPTSCN9A | |
| SCHEMBL14753226 | 0.76 | DPP4 (0.52) | DPP4DPP8NOTUMNAMPTCDK1 | |
| Trifluoroacetic Acid SCHEMBL28512172 | 0.76 | DPP4 (0.42) | DPP4DPP8NOTUMNAMPTSCN9A | |
| SCHEMBL30980046 | 0.76 | NAMPT (0.49) | DPP4DPP8NOTUMNAMPTSCN9A | |
| Trifluoroacetic Acid SCHEMBL25427998 | 0.75 | DPP4 (0.58) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL25428013 | 0.75 | DPP4 (0.48) | DPP4DPP8NOTUMNAMPTSCN9A | |
| SCHEMBL22977583 | 0.74 | DPP4 (0.49) | DPP4DPP8NOTUMNAMPTSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |