Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772785 | 1.00 | OPRD1 (0.39) | OPRD1OPRK1OPRM1OPRL1CYP2D6 | |
| SCHEMBL4303393 | 1.00 | OPRD1 (0.39) | OPRD1OPRK1OPRM1OPRL1CYP2D6 | |
| SCHEMBL15358903 | 1.00 | OPRD1 (0.39) | OPRD1OPRK1OPRM1OPRL1CYP2D6 | |
| SCHEMBL4294409 | 1.00 | OPRD1 (0.39) | OPRD1OPRK1OPRM1OPRL1CYP2D6 | |
| SCHEMBL25429324 | 1.00 | OPRD1 (0.39) | OPRD1OPRK1OPRM1OPRL1CYP2D6 | |
| SCHEMBL7003092 | 1.00 | OPRD1 (0.39) | OPRD1OPRK1OPRM1OPRL1CYP2D6 | |
| SCHEMBL5837912 | 0.89 | OPRD1 (0.42) | OPRD1OPRK1OPRM1OPRL1CYP2D6 | |
| SCHEMBL5837913 | 0.89 | OPRD1 (0.42) | OPRD1OPRK1OPRM1OPRL1CYP2D6 | |
| SCHEMBL25844736 | 0.88 | OPRD1 (0.39) | OPRD1OPRK1OPRM1OPRL1CYP2D6 | |
| SCHEMBL25428365 | 0.85 | OPRD1 (0.37) | OPRD1OPRK1OPRM1OPRL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023117681-A1 | HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-29 | — | — | WO | disclosed |