SCHEMBL2542934

SCHEMBL2542934

CC([SiH3])C(C)(C)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22975 0.73
SCHEMBL6578279 0.73
SCHEMBL7128934 0.72
SCHEMBL10297559 0.72
SCHEMBL9723481 0.70 TSHR (0.32)
SCHEMBL2148806 0.70
SCHEMBL29120507 0.70
Ammonia Solution, Strong SCHEMBL5901473 0.70
Tert-Butanol SCHEMBL15300416 0.70 ALDH1A1 (0.50)
SCHEMBL30692212 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1413181-A Novel hydrogenated naphthalene compounds prepared by rhodium-catalyzed ring opening reaction in the presence of phosphine ligands ASTRAZENECA AB (SE) 2003-04-23 CN claimed
US-5541079-A ESPECIALLY PESTICIDES STRATEGIC DIAGNOSTICS INC. 1996-07-30 US claimed
EP-0561758-A2 Method of preparing optically active homo-beta-amino acids MONSANTO COMPANY (US) 1993-09-22 EP claimed
EP-0479834-A4 MONOCLONAL AND POLYCLONAL ANTIBODIES AND TEST METHOD FOR DETERMINATION OF FENITROTHION AND CLOSELY RELATED ORGANOPHOSPHATES 1992-09-30 EP claimed
EP-0479834-A1 MONOCLONAL AND POLYCLONAL ANTIBODIES AND TEST METHOD FOR DETERMINATION OF FENITROTHION AND CLOSELY RELATED ORGANOPHOSPHATES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1992-04-15 EP claimed
WO-1991000294-A1 MONOCLONAL AND POLYCLONAL ANTIBODIES AND TEST METHOD FOR DETERMINATION OF FENITROTHION AND CLOSELY RELATED ORGANOPHOSPHATES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1991-01-10 WO claimed
EP-0396526-A2 Method of preparing chiral beta-amino acids MONSANTO COMPANY (US) 1990-11-07 EP claimed
US-20240158390-A1 OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV JANSSEN SCIENCES IRELAND UNLMITED COMPANY (IE) 2024-05-16 US disclosed
CN-113874380-A Other heteroaromatic compounds with anti-RSV activity 爱尔兰詹森科学公司 2021-12-31 CN disclosed
WO-2020234333-A1 OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV Janssen Sciences Ireland Unlimited Company (IE) 2020-11-26 WO disclosed
CN-103209981-B There is the heterocyclic fused imdazole derivatives of AMPK activation 盐野义制药株式会社 2016-12-28 CN disclosed
CN-1917881-B Novel phenylalanine derivatives AJINOMOTO KK 2014-11-26 CN disclosed
CN-101547906-B Antibacterial quinoline derivatives JANSSEN PHARMACEUTICA NV 2014-08-06 CN disclosed
CN-1042667-A Composite semipermeable membrane and manufacture method thereof SEPARATION DYNAMICS INC (US) 1990-06-06 CN disclosed
EP-0324377-A2 Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP disclosed
US-4833169-A MEMORY ACTIVATORS CIBA-GEIGY CORPORATION (US) 1989-05-23 US disclosed
CN-1032790-A Method and composition for immunizing plants against disease CIBA GEIGY AG (CH) 1989-05-10 CN disclosed
CN-88102628-A Novel substituted silylalkyleneamines 1988-11-30 CN disclosed
CN-86102077-A Carbonization penem intermediates preparation 1987-01-28 CN disclosed
CN-86102923-A The method for preparing antibiotic derivatives 1986-11-12 CN disclosed