Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25431152 | 0.79 | MKNK1 (0.59) | MKNK1MKNK2HCAR2HCAR3DRD4 | |
| SCHEMBL25339487 | 0.76 | MAPT (0.45) | MKNK1MKNK2HCAR2HCAR3IGF1R | |
| SCHEMBL27421814 | 0.72 | MEN1 (0.54) | MKNK1MKNK2HCAR2HCAR3DRD4 | |
| SCHEMBL29758358 | 0.71 | CA12 (0.46) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL29374702 | 0.71 | CA12 (0.46) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL1069905 | 0.71 | CA12 (0.46) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL4457723 | 0.70 | HCAR2 (0.43) | MKNK1MKNK2HCAR2HCAR3KMT2A | |
| SCHEMBL30558789 | 0.70 | MKNK1 (0.54) | MKNK1MKNK2HCAR2HCAR3ROCK2 | |
| SCHEMBL27977175 | 0.70 | MKNK1 (0.54) | MKNK1MKNK2HCAR2HCAR3ROCK2 | |
| SCHEMBL28820147 | 0.69 | HCAR2 (0.49) | MKNK1MKNK2HCAR2HCAR3IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250136559-A1 | SMO MODULATOR COMPOUNDS | Omass Therapeutics Limited (GB) | 2025-05-01 | — | — | US | disclosed |
| EP-4472959-A1 | SMO MODULATOR COMPOUNDS | Omass Therapeutics Limited (GB) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023148481-A1 | SMO MODULATOR COMPOUNDS | Omass Therapeutics Limited (GB) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023148481-A1 | SMO MODULATOR COMPOUNDS | Omass Therapeutics Limited (GB) | 2023-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250136559-A1 | SMO MODULATOR COMPOUNDS | SMO, SHH, GLI1 | MKNK1 1943/4885MKNK2 1543/4885HCAR2 811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.