Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | PADI4 | Q9UM07 | 8/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590362 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAHTTNPSR1PADI4 | |
| SCHEMBL25431384 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAHTTNPSR1PADI4 | |
| SCHEMBL30590350 | 0.90 | PADI4 (0.56) | SMN1; SMN2LMNAHTTNPSR1PADI4 | |
| SCHEMBL25431797 | 0.90 | PADI4 (0.56) | SMN1; SMN2LMNAHTTNPSR1PADI4 | |
| SCHEMBL30590388 | 0.90 | PADI4 (0.56) | SMN1; SMN2LMNAHTTNPSR1PADI4 | |
| SCHEMBL25434718 | 0.90 | PADI4 (0.56) | SMN1; SMN2LMNAHTTNPSR1PADI4 | |
| SCHEMBL25434711 | 0.90 | PADI4 (0.56) | SMN1; SMN2LMNAHTTNPSR1PADI4 | |
| SCHEMBL25431794 | 0.90 | PADI4 (0.56) | SMN1; SMN2LMNAHTTNPSR1PADI4 | |
| SCHEMBL25434667 | 0.87 | PADI4 (0.78) | SMN1; SMN2LMNAHTTNPSR1PADI4 | |
| SCHEMBL25434661 | 0.87 | PADI4 (0.78) | SMN1; SMN2LMNAHTTNPSR1PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482831-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | Satya Therapeutics, Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023161782-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | SATYARX PHARMA INNOVATIONS PVT LTD (IN) | 2023-08-31 | — | — | WO | disclosed |