Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 14/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25434661 | 1.00 | PADI4 (0.78) | PADI4MAPTNPC1RAB9ALMNA | |
| SCHEMBL30590395 | 1.00 | PADI4 (0.78) | PADI4MAPTNPC1RAB9ALMNA | |
| SCHEMBL22899635 | 0.90 | PADI4 (0.75) | PADI4MAPTNPC1RAB9ALMNA | |
| SCHEMBL31139840 | 0.88 | PADI4 (1.00) | PADI4MAPTNPC1RAB9ALMNA | |
| SCHEMBL19952818 | 0.88 | PADI4 (1.00) | PADI4MAPTNPC1RAB9ALMNA | |
| SCHEMBL29612117 | 0.88 | PADI4 (1.00) | PADI4MAPTNPC1RAB9ALMNA | |
| SCHEMBL25431384 | 0.87 | SMN1; SMN2 (0.61) | PADI4MAPTNPC1RAB9ALMNA | |
| SCHEMBL25431389 | 0.87 | SMN1; SMN2 (0.61) | PADI4MAPTNPC1RAB9ALMNA | |
| SCHEMBL30590362 | 0.87 | SMN1; SMN2 (0.61) | PADI4MAPTNPC1RAB9ALMNA | |
| SCHEMBL25433011 | 0.83 | PADI4 (0.56) | PADI4LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482831-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | Satya Therapeutics, Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023161782-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | SATYARX PHARMA INNOVATIONS PVT LTD (IN) | 2023-08-31 | — | — | WO | disclosed |