SCHEMBL2543142

SCHEMBL2543142

CC(C)c1ccc(C=C2SC(=O)NC2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PIM1 P11309 11/20 1.00
▸ MYC P01106 1/20 0.77
▸ MAX P61244 1/20 0.77
▸ PIM2 Q9P1W9 10/20 0.67
▸ HPGD P15428 2/20 0.67
▸ PIM3 Q86V86 1/20 0.64
▸ AKR1B1 P15121 2/20 0.62
▸ RAB9A P51151 2/20 0.62
▸ GSK3B P49841 2/20 0.62
▸ MAOA P21397 2/20 0.62
▸ TDP1 Q9NUW8 1/20 0.62
▸ MAOB P27338 1/20 0.62
▸ IGF1R P08069 2/20 0.61
▸ NPC1 O15118 1/20 0.61
▸ CISD1 Q9NZ45 2/20 0.60
▸ ALOX15 P16050 1/20 0.57
▸ PTGS2 P35354 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2543140 1.00 PIM1 (1.00) PIM1MYCMAXPIM2HPGD
SCHEMBL2543138 1.00 PIM1 (1.00) PIM1MYCMAXPIM2HPGD
SCHEMBL20816056 0.87 MYC (1.00) PIM1MYCMAXRAB9AMAOA
SCHEMBL8179067 0.87 MYC (1.00) PIM1MYCMAXRAB9AMAOA
SCHEMBL8179068 0.87 MYC (1.00) PIM1MYCMAXRAB9AMAOA
SCHEMBL9375625 0.87 PIM1 (0.77) PIM1MYCMAXPIM2HPGD
SCHEMBL9375624 0.87 PIM1 (0.77) PIM1MYCMAXPIM2HPGD
SCHEMBL8187521 0.83 PIM1 (0.70) PIM1MYCMAXPIM2HPGD
SCHEMBL23036923 0.82 MTOR (0.80) PIM1MYCMAXPIM2HPGD
SCHEMBL8001434 0.80 AKR1B1 (0.71) PIM1PIM2HPGDPIM3AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180202110-A1 CHEMICAL COMPOSITION FOR ANTI-CORROSION MINERAL PAPER CHENG KIT YEW NELSON (SG) 2018-07-19 — — US claimed
EP-3329047-A1 CHEMICAL COMPOSITION FOR ANTI-CORROSION MINERAL PAPER Cheng Kit Yew, Nelson (SG) 2018-06-06 — — EP claimed
CN-112385019-B Etchant composition 朗姆研究公司 2025-04-29 — — CN disclosed
US-11345852-B2 Etchant composition LAM RESEARCH CORPORATION (US) 2022-05-31 — — US disclosed
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 — — EP disclosed
US-20210277308-A1 ETCHANT COMPOSITION LAM RESEARCH AG (AT) 2021-09-09 — — US disclosed
US-20180202110-A1 CHEMICAL COMPOSITION FOR ANTI-CORROSION MINERAL PAPER CHENG KIT YEW NELSON (SG) 2018-07-19 — — US disclosed
EP-3329047-A1 CHEMICAL COMPOSITION FOR ANTI-CORROSION MINERAL PAPER Cheng Kit Yew, Nelson (SG) 2018-06-06 — — EP disclosed
US-9272388-B2 Polishing systems NEXPLANAR CORPORATION (US) 2016-03-01 — — US disclosed
US-20130196173-A1 Organic Corrosion Inhibitor-Embedded Polymer Capsule, Preparation Method Thereof, Composition Containing Same, and Surface Treated Steel Sheet Using Same POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-08-01 — — US disclosed
US-20130149945-A1 POLISHING SYSTEMS CMC MATERIALS LLC 2013-06-13 — — US disclosed
US-8383003-B2 Polishing systems NEXPLANAR CORPORATION (US) 2013-02-26 — — US disclosed
US-20110263664-A1 Inhibitors of PIM-1 Protein Kinases, Compositions and Methods for Treating Prostate Cancer MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2011-10-27 — — US disclosed
EP-2217235-A2 INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER Musc Foundation for Research Development (US) 2010-08-18 — — EP disclosed
US-20090318063-A1 Polishing systems NEXPLANAR CORPORATION (US) 2009-12-24 — — US disclosed
US-7564614-B2 Electrode protection film for electrophoretic displays SIPIX IMAGING, INC. (US) 2009-07-21 — — US disclosed
WO-2009064486-A9 INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER MUSC FOUND FOR RES DEV (US) 2009-07-16 — — WO disclosed
WO-2009064486-A2 INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2009-05-22 — — WO disclosed
US-20050264869-A1 Electrode protection film for electrophoretic displays E INK CALIFORNIA, LLC 2005-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263664-A1 Inhibitors of PIM-1 Protein Kinases, Compositions and Methods for Treating Prostate Cancer PIM1, PIM2, PIM3 PIM1 1/4885MYC 4/4885MAX 756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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