Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 3/20 | 1.00 |
| ▸ | MAX | P61244 | 3/20 | 1.00 |
| ▸ | PIM1 | P11309 | 1/20 | 0.77 |
| ▸ | NAT1 | P18440 | 6/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | CRHBP | P24387 | 1/20 | 0.65 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.65 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.65 |
| ▸ | CLK1 | P49759 | 1/20 | 0.65 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.65 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.65 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20816056 | 1.00 | MYC (1.00) | MYCMAXPIM1NAT1MTOR | |
| SCHEMBL8179067 | 1.00 | MYC (1.00) | MYCMAXPIM1NAT1MTOR | |
| SCHEMBL2543142 | 0.87 | PIM1 (1.00) | MYCMAXPIM1CISD1NPC1 | |
| SCHEMBL2543140 | 0.87 | PIM1 (1.00) | MYCMAXPIM1CISD1NPC1 | |
| SCHEMBL2543138 | 0.87 | PIM1 (1.00) | MYCMAXPIM1CISD1NPC1 | |
| SCHEMBL4058338 | 0.86 | MMP3 (0.73) | MYCMAXPIM1NPC1RAB9A | |
| SCHEMBL4057818 | 0.86 | MYC (0.73) | MYCMAXPIM1NAT1MTOR | |
| SCHEMBL4058340 | 0.86 | MMP3 (0.73) | MYCMAXPIM1NPC1RAB9A | |
| SCHEMBL4055287 | 0.86 | MMP3 (0.73) | MYCMAXPIM1NPC1RAB9A | |
| SCHEMBL4057820 | 0.86 | MYC (0.73) | MYCMAXPIM1NAT1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190085404-A1 | METHODS OF IDENTIFYING AND TREATING IMMUNE CHECKPOINT INHIBITOR-RESPONSIVE NEOPLASMS AND CELLS, TRANSGENIC ANIMALS AND KITS FOR USE THEREIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2019-03-21 | — | — | US | disclosed |
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |