SCHEMBL25431905

SCHEMBL25431905

CCC(=O)N1N=C(c2c(C)c3ccsc3[nH]c2=O)CC1c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ RAD51 Q06609 4/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ ATM Q13315 1/20 0.53
▸ MEN1 O00255 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ TERT O14746 1/20 0.47
▸ GRIN2D O15399 1/20 0.46
▸ GRIN2C Q14957 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25432110 0.93 MEN1 (0.58) RAD51KDM4EMEN1KMT2AGRIN2D
SCHEMBL26064225 0.93 MEN1 (0.58) RAD51KDM4EMEN1KMT2AGRIN2D
SCHEMBL26064226 0.93 MEN1 (0.58) RAD51KDM4EMEN1KMT2AGRIN2D
SCHEMBL25433024 0.92 MEN1 (0.50) RAD51KDM4EATMMEN1KMT2A
SCHEMBL25434505 0.91 MEN1 (0.49) RAD51KDM4EATMMEN1KMT2A
SCHEMBL26064198 0.91 RAD51 (0.58) RAD51MEN1KMT2A
SCHEMBL25432658 0.91 RAD51 (0.55) RAD51KDM4EMEN1KMT2A
SCHEMBL25432966 0.91 RAD51 (0.58) RAD51MEN1KMT2A
SCHEMBL25431800 0.91 MEN1 (0.49) RAD51KDM4EATMMEN1KMT2A
SCHEMBL26064199 0.91 RAD51 (0.58) RAD51MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145601-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYA THERAPEUTICS, INC. 2025-05-08 — — US claimed
EP-4482831-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS Satya Therapeutics, Inc. (US) 2025-01-01 — — EP claimed
WO-2023161782-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYARX PHARMA INNOVATIONS PVT LTD (IN) 2023-08-31 — — WO claimed
US-20250145601-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYA THERAPEUTICS, INC. 2025-05-08 — — US disclosed
EP-4482831-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS Satya Therapeutics, Inc. (US) 2025-01-01 — — EP disclosed
CN-118696034-A Novel bicyclic compounds as RAD51 inhibitors 萨提亚疗法股份有限公司 2024-09-24 — — CN disclosed
WO-2023161782-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYARX PHARMA INNOVATIONS PVT LTD (IN) 2023-08-31 — — WO disclosed
WO-2023161782-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYARX PHARMA INNOVATIONS PVT LTD (IN) 2023-08-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145601-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS RAD51, ERCC4, ERCC2 RAD51 1/4885KDM4E 3731/4885ATM 290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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