SCHEMBL26064225

SCHEMBL26064225

CCC(=O)N1N=C(c2c(C)c3ccsc3[nH]c2=O)C[C@@H]1c1ccc(C)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.58
▸ KMT2A Q03164 3/20 0.58
▸ RAD51 Q06609 3/20 0.49
▸ KDM4E B2RXH2 3/20 0.48
▸ ALDH1A1 P00352 2/20 0.48
▸ GLA P06280 2/20 0.48
▸ GAA P10253 2/20 0.48
▸ PKM P14618 2/20 0.48
▸ HPGD P15428 1/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ YAP1 P46937 1/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ TEAD4 Q15561 1/20 0.48
▸ GRIN2D O15399 1/20 0.46
▸ GRIN2C Q14957 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26064226 1.00 MEN1 (0.58) MEN1KMT2ARAD51KDM4EALDH1A1
SCHEMBL25432110 1.00 MEN1 (0.58) MEN1KMT2ARAD51KDM4EALDH1A1
SCHEMBL26064198 0.93 RAD51 (0.58) MEN1KMT2ARAD51
SCHEMBL25434505 0.93 MEN1 (0.49) MEN1KMT2ARAD51KDM4EALDH1A1
SCHEMBL26064199 0.93 RAD51 (0.58) MEN1KMT2ARAD51
SCHEMBL25432658 0.93 RAD51 (0.55) MEN1KMT2ARAD51KDM4EALDH1A1
SCHEMBL25432966 0.93 RAD51 (0.58) MEN1KMT2ARAD51
SCHEMBL25431800 0.93 MEN1 (0.49) MEN1KMT2ARAD51KDM4EALDH1A1
SCHEMBL25431905 0.93 RAD51 (0.53) MEN1KMT2ARAD51KDM4EGRIN2D
SCHEMBL25433024 0.92 MEN1 (0.50) MEN1KMT2ARAD51KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145601-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYA THERAPEUTICS, INC. 2025-05-08 — — US claimed
WO-2023161782-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYARX PHARMA INNOVATIONS PVT LTD (IN) 2023-08-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145601-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS RAD51, ERCC4, ERCC2 MEN1 1316/4885KMT2A 2879/4885RAD51 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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