Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15661401 | 0.81 | MAPT (0.53) | RAB9AL3MBTL1KDM4ESMN1; SMN2EPHX1 | |
| SCHEMBL5034247 | 0.80 | POLB (0.55) | RAB9AL3MBTL1KDM4ESMN1; SMN2HTT | |
| SCHEMBL202170 | 0.79 | RXFP1 (0.58) | MDM2RAB9AL3MBTL1KDM4EBCHE | |
| SCHEMBL334233 | 0.77 | BCHE (0.61) | MDM2RAB9AL3MBTL1KDM4EBCHE | |
| SCHEMBL18920315 | 0.77 | MDM2 (0.59) | MDM2RAB9AL3MBTL1KDM4EBCHE | |
| SCHEMBL24324494 | 0.76 | HTT (0.58) | RAB9AL3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL13589544 | 0.75 | MDM2 (0.61) | MDM2RAB9AL3MBTL1KDM4EBCHE | |
| SCHEMBL11534363 | 0.74 | MAPT (0.66) | MDM2RAB9AL3MBTL1BCHELMNA | |
| SCHEMBL28787047 | 0.72 | MDM2 (0.64) | MDM2RAB9AL3MBTL1KDM4EBCHE | |
| SCHEMBL26785462 | 0.72 | NPC1 (0.46) | RAB9AL3MBTL1KDM4ESMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065616-B1 | POLYMER CONETWORKS OF POLY(PYRIDINE-(METH)-ACRYLAMIDE) DERIVATIVES-CROSSLINKED BY TRANSITION METAL IONS- AND LINKED BY POLYDIMETHYLSILOXANE DERIVATIVES | LUXEMBOURG INST SCIENCE & TECH LIST (LU) | 2023-08-23 | — | — | EP | disclosed |
| CN-114761447-A | Polymer networks of poly (pyridine- (meth) -acrylamide) derivatives crosslinked by transition metal ions and linked by polydimethylsiloxane derivatives | 卢森堡科学技术研究院 | 2022-07-15 | — | — | CN | disclosed |