Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 15/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25433253 | 1.00 | CDC25A (0.57) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 | |
| SCHEMBL25432900 | 0.81 | CDC25A (0.42) | CDC25ACDC25BGPBAR1AKR1B10AKR1B1 | |
| SCHEMBL25432898 | 0.81 | CDC25A (0.42) | CDC25ACDC25BGPBAR1AKR1B10AKR1B1 | |
| SCHEMBL18271594 | 0.81 | CDC25A (0.63) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL10857860 | 0.81 | CDC25A (0.63) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL10857773 | 0.81 | CDC25A (0.63) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL9679574 | 0.81 | CDC25A (0.56) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL9718353 | 0.81 | CDC25A (0.56) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL15494063 | 0.78 | CDC25A (0.69) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 | |
| SCHEMBL10125341 | 0.78 | CDC25A (0.69) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486441-A1 | SILA-ANALOGUES OF VITAMIN D COMPOUNDS, METHOD OF PRODUCING SAID COMPOUNDS AND USES THEREOF | REQUIMTE - Rede de Química e Tecnologia (PT) | 2025-01-08 | — | — | EP | disclosed |
| WO-2023161688-A1 | SILA-ANALOGUES OF VITAMIN D COMPOUNDS, METHOD OF PRODUCING SAID COMPOUNDS AND USES THEREOF | REQUIMTE - REDE DE QUÍMICA E TECNOLOGIA (PT) | 2023-08-31 | — | — | WO | disclosed |