Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.56 |
| ▸ | CDC25B | P30305 | 2/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 11/20 | 0.41 |
| ▸ | OSBP | P22059 | 1/20 | 0.36 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679574 | 1.00 | CDC25A (0.56) | CDC25ACDC25BGPBAR1OSBPOSBP2 | |
| SCHEMBL8359291 | 0.94 | CDC25A (0.49) | CDC25ACDC25BGPBAR1OSBPOSBP2 | |
| SCHEMBL13556511 | 0.84 | CDC25A (0.43) | CDC25ACDC25BGPBAR1 | |
| SCHEMBL16151557 | 0.84 | CDC25A (0.43) | CDC25ACDC25BGPBAR1 | |
| SCHEMBL25433253 | 0.81 | CDC25A (0.57) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL25433251 | 0.81 | CDC25A (0.57) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL18271594 | 0.80 | CDC25A (0.63) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL10857773 | 0.80 | CDC25A (0.63) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL10857860 | 0.80 | CDC25A (0.63) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL17888102 | 0.77 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326875-B1 | DIDEHYDRO-VITAMIN D3 DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-25 | — | — | EP | disclosed |
| EP-0326875-A1 | Didehydro-vitamin D3 derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-08-09 | — | — | EP | disclosed |
| US-4804502-A | TREATMENT OF CALCIUM DEFICIENCY DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1989-02-14 | — | — | US | disclosed |