Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31609624 | 1.00 | POLB (0.59) | POLBSMN1; SMN2HRH4HRH3ROCK2 | |
| SCHEMBL1612954 | 0.76 | HRH3 (0.72) | POLBSMN1; SMN2HRH4HRH3 | |
| SCHEMBL25373058 | 0.74 | GPR35 (0.51) | SMN1; SMN2HPGDTSHR | |
| SCHEMBL3253717 | 0.74 | POLB (1.00) | POLBSMN1; SMN2HRH4HRH3 | |
| SCHEMBL31609598 | 0.73 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDTSHRESR2 | |
| SCHEMBL25433906 | 0.73 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDTSHRESR2 | |
| SCHEMBL2770082 | 0.72 | HRH4 (0.71) | POLBSMN1; SMN2HRH4HRH3 | |
| SCHEMBL11611858 | 0.72 | POLB (0.55) | POLBSMN1; SMN2HRH3HPGDTSHR | |
| SCHEMBL25431128 | 0.72 | POLB (0.59) | POLBSMN1; SMN2HRH4HRH3SYK | |
| SCHEMBL31428828 | 0.72 | POLB (0.59) | POLBSMN1; SMN2HRH4HRH3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482583-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023161316-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023161316-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-31 | — | — | WO | disclosed |