Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.63 |
| ▸ | F3 | P13726 | 1/20 | 0.63 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.63 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.63 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.63 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL5712651 | 0.83 | F7 (0.85) | F7F3SARM1SIRT2SIRT6 | |
| Agmatine SCHEMBL23297269 | 0.82 | F7 (0.54) | F7F3SARM1SIRT2SIRT6 | |
| Spermidine SCHEMBL5555910 | 0.82 | TSHR (0.55) | GRIA1CYP3A4 | |
| Niacinamide SCHEMBL27626287 | 0.81 | F7 (0.65) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28756091 | 0.81 | F7 (0.69) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28390244 | 0.81 | F7 (0.69) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL10897800 | 0.79 | EPHX2 (0.66) | CYP3A4THRBHDAC1HDAC3ALDH1A1 | |
| Niacinamide SCHEMBL460466 | 0.79 | F7 (1.00) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL2926 | 0.79 | — | — | |
| Niacinamide SCHEMBL19978192 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293453-A1 | SPERMIDINE AND USES THEREOF | TLL THE LONGEVITY LABS GMBH (AT) | 2023-09-21 | — | — | US | disclosed |