Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipentylamine SCHEMBL28181756 | 0.83 | NAAA (0.58) | TSHRPOLBCYP3A4PARP1MAPT | |
| Spermidine SCHEMBL25434620 | 0.82 | F7 (0.63) | CYP3A4GRIA1 | |
| SCHEMBL15065079 | 0.81 | GRIN1 (0.63) | GRIN1GRIN2AGRIN2BGRIA1 | |
| SCHEMBL15065078 | 0.80 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL12085668 | 0.80 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2BGRIA1 | |
| Benzoic Acid SCHEMBL5547336 | 0.80 | GRIN1 (0.47) | TSHRGRIN1GRIN2AGRIN2BGRIA1 | |
| Benzamide SCHEMBL28182470 | 0.79 | CYP3A4 (0.59) | TSHRPOLBCYP3A4PARP1MAPT | |
| SCHEMBL16577153 | 0.78 | MAOA (0.53) | CYP3A4MAPTTDP1L3MBTL1GRIN1 | |
| SCHEMBL5547338 | 0.78 | TDP1 (0.62) | TDP1GRIN1GRIN2AGRIN2BLMNA | |
| Benzamide SCHEMBL14574628 | 0.77 | LMNA (0.61) | TSHRPOLBCYP3A4PARP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070202047-A1 | Polyamine-substituted ligands for use as contrast agents | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070202047-A1 | Polyamine-substituted ligands for use as contrast agents | HNRNPH3, HRH3, HCAR3 | TSHR 206/4885POLB 3489/4885CYP3A4 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.