Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.64 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | PNLIP | P16233 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25436073 | 1.00 | PTPN2 (0.64) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 | |
| SCHEMBL25433754 | 1.00 | PTPN2 (0.64) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 | |
| SCHEMBL25434992 | 1.00 | PTPN2 (0.64) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 | |
| SCHEMBL25396294 | 0.86 | PTPN2 (0.67) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 | |
| SCHEMBL6783507 | 0.86 | PTPN2 (0.67) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 | |
| SCHEMBL6783502 | 0.86 | PTPN2 (0.67) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 | |
| SCHEMBL25395895 | 0.86 | PTPN2 (0.67) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 | |
| SCHEMBL25394431 | 0.86 | PTPN2 (0.67) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 | |
| SCHEMBL24422153 | 0.79 | PTPN1 (1.00) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 | |
| SCHEMBL30288170 | 0.79 | PTPN1 (0.81) | PTPN2PTPN1RPS6KA5MAPKAPK2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156429-A1 | PROCESS FOR PREPARING OCTAHYDRO-2(1H)-NAPHTHALENONE DERIVATIVES | FIRMENICH SA (CH) | 2023-08-24 | — | — | WO | disclosed |