Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 2/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.67 |
| ▸ | PNLIP | P16233 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25396294 | 1.00 | PTPN2 (0.67) | PTPN2PTPN1PNLIPTRPA1CHRNB2 | |
| SCHEMBL25395895 | 1.00 | PTPN2 (0.67) | PTPN2PTPN1PNLIPTRPA1CHRNB2 | |
| SCHEMBL6783507 | 1.00 | PTPN2 (0.67) | PTPN2PTPN1PNLIPTRPA1CHRNB2 | |
| SCHEMBL25394431 | 1.00 | PTPN2 (0.67) | PTPN2PTPN1PNLIPTRPA1CHRNB2 | |
| SCHEMBL25433754 | 0.86 | PTPN2 (0.64) | PTPN2PTPN1PNLIPTRPA1CHRNB2 | |
| SCHEMBL25434992 | 0.86 | PTPN2 (0.64) | PTPN2PTPN1PNLIPTRPA1CHRNB2 | |
| SCHEMBL25435120 | 0.86 | PTPN2 (0.64) | PTPN2PTPN1PNLIPTRPA1CHRNB2 | |
| SCHEMBL25436073 | 0.86 | PTPN2 (0.64) | PTPN2PTPN1PNLIPTRPA1CHRNB2 | |
| SCHEMBL24422153 | 0.80 | PTPN1 (1.00) | PTPN2PTPN1PNLIPTRPA1CHRNB2 | |
| SCHEMBL30288170 | 0.80 | PTPN1 (0.81) | PTPN2PTPN1PNLIPTRPA1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727277-B1 | BENZO(A)XANTHENE DERIVATIVES; LYMPHATIC ABSORPTION INTENSIFIERS 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE INHIBITORS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION | 2004-04-27 | — | — | US | disclosed |