⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846465 | 0.65 | — | — | |
| SCHEMBL23356553 | 0.62 | — | — | |
| SCHEMBL6236249 | 0.59 | P2RX7 (0.31) | — | |
| SCHEMBL25435304 | 0.59 | — | — | |
| SCHEMBL30994187 | 0.58 | PREP (0.39) | — | |
| SCHEMBL21035016 | 0.58 | CYP3A4 (0.35) | — | |
| SCHEMBL16099945 | 0.57 | — | — | |
| SCHEMBL31219415 | 0.56 | — | — | |
| Acetic Acid SCHEMBL15874733 | 0.55 | FFAR3 (0.33) | — | |
| SCHEMBL2417620 | 0.55 | FFAR3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |