Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.57 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31323332 | 1.00 | KRAS (0.57) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25404453 | 0.93 | KRAS (0.58) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25414507 | 0.92 | KRAS (0.53) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30758946 | 0.91 | KRAS (0.52) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25401862 | 0.91 | KRAS (0.58) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25401109 | 0.91 | KRAS (0.52) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31323342 | 0.91 | KRAS (0.68) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL27243298 | 0.91 | KRAS (0.68) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31662384 | 0.90 | KRAS (0.48) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL29679922 | 0.90 | KRAS (0.59) | KRASMAPK3MAPK1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138583-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |