SCHEMBL25435779

SCHEMBL25435779

N#Cc1ccc(-c2noc(N3CCC(C(=O)NCC4CCNC4)CC3)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.53
▸ LMNA P02545 2/20 0.47
▸ MEN1 O00255 4/20 0.45
▸ KMT2A Q03164 4/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ KDM1A O60341 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25439425 0.99 MAPT (0.53) MAPTLMNAMEN1KMT2ASMN1; SMN2
Trifluoroacetic Acid SCHEMBL31546415 0.94 MAPT (0.49) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL25401980 0.89 MAPT (0.55) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL25434651 0.89 MAPT (0.55) MAPTLMNAMEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL25435613 0.88 MAPT (0.54) MAPTLMNAMEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL25435609 0.88 MAPT (0.54) MAPTLMNAMEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL25438946 0.88 MAPT (0.54) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL25403814 0.87 LMNA (0.61) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL25401737 0.87 LMNA (0.61) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL25435629 0.87 LMNA (0.61) MAPTLMNAMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MAPT 2999/4885LMNA 1344/4885MEN1 1569/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MAPT 2999/4885LMNA 1344/4885MEN1 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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