Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15693459 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1BLMTSHRSLC22A2 | |
| SCHEMBL17586597 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1BLMTSHRSLC22A2 | |
| SCHEMBL2068478 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1BLMTSHRSLC22A2 | |
| SCHEMBL1238391 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1BLMTDP1CYP1A2 | |
| SCHEMBL29650409 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1BLMTDP1CYP1A2 | |
| SCHEMBL4463910 | 0.70 | ALDH1A1 (0.44) | SMN1; SMN2L3MBTL1BLMTSHRSLC22A2 | |
| SCHEMBL13342069 | 0.69 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1BLMALOX15TDP1 | |
| SCHEMBL22472908 | 0.69 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1BLMSLC22A2SLC22A1 | |
| SCHEMBL12705444 | 0.69 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1BLMTSHRSLC22A2 | |
| Acetonitrile SCHEMBL2818707 | 0.69 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1BLMCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125681-A1 | HETEROCYCLIC COMPOUNDS | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |