Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL11050258 | 0.97 | TLR8 (0.57) | TLR8CNR2NPC1CNR1CASR | |
| SCHEMBL28377075 | 0.80 | TLR8 (0.62) | TLR8CNR2NPC1TSHRSMN1; SMN2 | |
| SCHEMBL8016313 | 0.79 | TLR8 (0.67) | TLR8CASRTSHRSMN1; SMN2KDM4E | |
| SCHEMBL1942206 | 0.79 | PARP1 (0.45) | TLR8PARP1 | |
| SCHEMBL27847996 | 0.76 | ALDH1A1 (0.56) | TLR8CNR2NPC1TSHRSMN1; SMN2 | |
| SCHEMBL28378028 | 0.76 | TLR8 (0.63) | TLR8CNR2NPC1TSHRSMN1; SMN2 | |
| SCHEMBL16486950 | 0.75 | TLR8 (1.00) | TLR8 | |
| SCHEMBL28372897 | 0.75 | TLR8 (0.64) | TLR8CNR2TSHRSMN1; SMN2 | |
| SCHEMBL28373626 | 0.75 | TLR8 (0.64) | TLR8CNR2TSHRSMN1; SMN2 | |
| SCHEMBL28378368 | 0.75 | TLR8 (0.64) | TLR8CNR2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |