SCHEMBL25436732

SCHEMBL25436732

O=C(O)NS(=O)(=O)c1ccccc1C(F)(F)F

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
ALDH1A1 P00352 1/20 0.60
ALKBH2 Q6NS38 1/20 0.56
ALKBH3 Q96Q83 1/20 0.56
FTO Q9C0B1 1/20 0.56
SLC22A12 Q96S37 10/20 0.54
KAT6A Q92794 1/20 0.54
RXFP1 Q9HBX9 1/20 0.50
MMP7 P09237 1/20 0.50
CYP2C9 P11712 2/20 0.48
SLC22A6 Q4U2R8 2/20 0.48
SLC22A8 Q8TCC7 2/20 0.48
SLC22A11 Q9NSA0 2/20 0.48
GAA P10253 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10918400 0.83 SLC22A12 (0.54) MEN1KMT2AALDH1A1ALKBH2ALKBH3
SCHEMBL30591430 0.82 MEN1 (0.52) MEN1KMT2AALDH1A1ALKBH2ALKBH3
SCHEMBL9212071 0.82 MEN1 (0.52) MEN1KMT2AALDH1A1ALKBH2ALKBH3
SCHEMBL30009742 0.81 HIF1A (0.51) MEN1KMT2AALDH1A1ALKBH2ALKBH3
SCHEMBL29536289 0.80 SLC22A12 (0.58) MEN1KMT2AALDH1A1SLC22A12KAT6A
SCHEMBL1767681 0.80 SLC22A12 (0.58) MEN1KMT2AALDH1A1SLC22A12KAT6A
SCHEMBL14676717 0.79 MEN1 (0.56) MEN1KMT2AALDH1A1ALKBH2ALKBH3
SCHEMBL17698979 0.78 SLC22A12 (0.60) MEN1KMT2AALDH1A1SLC22A12KAT6A
SCHEMBL3769130 0.77 SLC22A12 (0.70) MEN1KMT2AALDH1A1SLC22A12CYP2C9
SCHEMBL4029025 0.77 SLC22A12 (0.58) MEN1KMT2AALDH1A1SLC22A12KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4341246-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2024-03-27 EP disclosed
WO-2023177568-A1 CANNABINOID RECEPTOR MODULATING COMPOUNDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-09-21 WO disclosed