Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.46 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212071 | 0.85 | MEN1 (0.52) | KMT2AMEN1ALDH1A1ALKBH2ALKBH3 | |
| SCHEMBL30591430 | 0.85 | MEN1 (0.52) | KMT2AMEN1ALDH1A1ALKBH2ALKBH3 | |
| SCHEMBL10686865 | 0.81 | NR1H4 (0.44) | KMT2ASLC22A12NR1H4GAA | |
| SCHEMBL11851628 | 0.81 | GAA (0.49) | HIF1AALDH1A1ALKBH2ALKBH3KAT6A | |
| SCHEMBL25436732 | 0.81 | MEN1 (0.60) | KMT2AMEN1ALDH1A1ALKBH2ALKBH3 | |
| Benzene SCHEMBL10690567 | 0.80 | KMT2A (0.46) | KMT2AMEN1SLC22A12NR1H4GAA | |
| SCHEMBL30591358 | 0.79 | KMT2A (0.48) | KMT2AMEN1ALDH1A1ALKBH2ALKBH3 | |
| SCHEMBL9074960 | 0.78 | TSHR (0.47) | KMT2AALDH1A1GAA | |
| SCHEMBL9789350 | 0.78 | HTT (0.53) | HIF1AALDH1A1GAA | |
| SCHEMBL9074962 | 0.77 | CA12 (0.58) | KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341246-A1 | A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES | The United States of America, as represented by The Secretary, Department of Health and Human Services (US) | 2024-03-27 | — | — | EP | disclosed |
| WO-2022245627-A1 | A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-11-24 | — | — | WO | disclosed |