Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2543391 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL29702383 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL28486962 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL2545037 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| Potassium Ion SCHEMBL2544031 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL28675308 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL28493992 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL2544026 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL20139441 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL7870419 | 0.94 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104532386-B | Polylactic acid filter stick paper element and manufacturing method thereof | 红塔烟草(集团)有限责任公司 | 2017-03-22 | — | — | CN | claimed |
| CN-104194295-B | A kind of abnormity Lyocell fiber strengthens lactic acid composite material and preparation method thereof | 东华大学 | 2016-08-24 | — | — | CN | claimed |
| CN-104532386-A | Polylactic acid filter stick paper element and manufacturing method thereof | HONGTA TOBACCO GROUP CO LTD | 2015-04-22 | — | — | CN | claimed |
| CN-106046722-B | Complete biodegradable bionic fish bait and preparation method thereof | 威海两岸环保新材料科技有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-104532386-B | Polylactic acid filter stick paper element and manufacturing method thereof | 红塔烟草(集团)有限责任公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-106046722-A | Fully biodegradable bionic bait and preparation method thereof | 威海两岸环保新材料科技有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-104532386-A | Polylactic acid filter stick paper element and manufacturing method thereof | HONGTA TOBACCO GROUP CO LTD | 2015-04-22 | — | — | CN | disclosed |
| CN-104194295-A | Profiled Lyocell fiber reinforced polylactic acid composite material and preparation method thereof | NAT UNIV DONG HWA | 2014-12-10 | — | — | CN | disclosed |
| US-8288497-B2 | Synthesis of poly-(P-aryleneethynylene)s in neat water under aerobic conditions | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-10-16 | — | — | US | disclosed |
| US-20110257356-A1 | Synthesis of Poly-(P-Aryleneethynylene)s in Neat Water Under Aerobic Conditions | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-10-20 | — | — | US | disclosed |
| US-20090326150-A1 | SYNTHESIS OF POLY-(P-ARYLENEETHYNYLENE)S IN NEAT WATER UNDER AEROBIC CONDIT | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-12-31 | — | — | US | disclosed |