Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25436911 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3967181 | 0.82 | SLC6A9 (0.40) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL29299508 | 0.82 | SLC6A9 (0.40) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL1165366 | 0.82 | SLC6A9 (0.40) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL7744888 | 0.82 | SLC6A9 (0.40) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL14100030 | 0.82 | SLC6A9 (0.40) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL13223389 | 0.82 | SLC6A9 (0.40) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL24220960 | 0.82 | SLC6A9 (0.40) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL1133814 | 0.82 | — | — | |
| SCHEMBL22345732 | 0.82 | EPHX2 (0.40) | ALDH1A1KDM4EPOLBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |