Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 18/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27211590 | 0.87 | DGAT2 (0.73) | DGAT2KMT2A | |
| SCHEMBL29511888 | 0.87 | DGAT2 (0.73) | DGAT2KMT2A | |
| SCHEMBL29512127 | 0.85 | DGAT2 (0.76) | DGAT2KMT2A | |
| SCHEMBL27211604 | 0.85 | DGAT2 (0.76) | DGAT2KMT2A | |
| SCHEMBL29511980 | 0.85 | DGAT2 (0.70) | DGAT2KMT2A | |
| SCHEMBL25350660 | 0.85 | DGAT2 (0.70) | DGAT2KMT2A | |
| SCHEMBL25352630 | 0.85 | DGAT2 (0.76) | DGAT2KMT2A | |
| SCHEMBL25351890 | 0.85 | DGAT2 (0.76) | DGAT2KMT2A | |
| SCHEMBL29511940 | 0.85 | DGAT2 (0.76) | DGAT2KMT2A | |
| SCHEMBL29511900 | 0.85 | DGAT2 (0.76) | DGAT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225739-A1 | PREPARATION OF BENZIMIDAZOLONE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2023-08-16 | — | — | EP | disclosed |