SCHEMBL2543900

SCHEMBL2543900

CC1(N)C=CC(c2ccc(N)cc2)C=C1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
ACHE P22303 1/20 0.32
CYP19A1 P11511 2/20 0.32
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714827 0.73 MAOA (0.35) MEN1MAPTKMT2ACYP19A1
SCHEMBL16317354 0.72 MEN1 (0.44) MEN1MAPTKMT2AACHECYP19A1
SCHEMBL5017276 0.72 MEN1 (0.31) MEN1MAPTKMT2ACYP19A1
SCHEMBL7169778 0.67 MAPT (0.36) MEN1MAPTKMT2ACYP19A1
SCHEMBL22335046 0.65 KDM1A (0.65) MEN1MAPTKMT2ACYP19A1
SCHEMBL20707778 0.62 KDM1A (0.45) MEN1MAPTKMT2AACHECYP19A1
SCHEMBL20707745 0.62 KDM1A (0.45) MEN1MAPTKMT2AACHECYP19A1
SCHEMBL20707920 0.62 MAPT (0.38) MEN1MAPTKMT2AACHECYP19A1
SCHEMBL38656156 0.62 KDM1A (0.45) MEN1MAPTKMT2AACHECYP19A1
SCHEMBL1074533 0.62 KDM1A (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8512700-B2 Antibody protective agent and methods of using same JIANGNAN UNIVERSITY (CN) 2013-08-20 US disclosed
US-20110262626-A1 Antibody Protective Agent And Methods Of Using Same JIANGNAN UNIVERSITY (CN) 2011-10-27 US disclosed
US-4242258-A TETRAKISAZO, BLACK HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-30 US disclosed